Q10 is a key element in the cellular energy turnover and also serves as a protective antioxidant. The human body is able to make most of its own Q10 but as we grow older, our endogenous Q10 synthesis decreases, and this is also the case with certain diseases and as a result of using specific types of medicine. A large meta-analysis has shown that Q10 supplementation is able to reduce chronic fatigue in healthy individuals as well as in people with diseases. Apparently, taking larger doses for longer periods of time works best for energy levels. It is important to choose a Q10 supplement that has the right quality and comes with documentation to ensure that the Q10 molecules are absorbed properly in the blood and reach the energy-producing powerhouses of the cells.

Chronic fatigue is quite common, and it is not simply a matter of too little sleep and too much work. Japanese researchers have found that low levels of vitamin B12 and folate (vitamin B9) may contribute to increasing fatigue and lack of motivation in otherwise healthy individuals. The Japanese study was published in the journal Nutrients.

Side effects such as chronic fatigue syndrome (CFS/ME), brain fog, sleep disturbances, and other neurological issues have been observed both after COVID-19 infections and vaccinations. According to a study published in Nutrition, most of these patients were already deficient in vitamin D, and higher doses of vitamin D that optimize blood levels can help relieve their symptoms. It’s generally advisable to maintain adequate vitamin D levels for the prevention of COVID-19, influenza, and other infections.