The body’s metabolism encompasses all processes that convert food into energy, as well as those that maintain stable blood sugar levels, normal lipid balance, and normal blood pressure. Metabolic health is therefore crucial in the prevention and management of a range of lifestyle-related diseases. Selenium plays a key role through various enzymatic processes and as a protective antioxidant. Since selenium deficiency is widespread, a team of researchers has reviewed a number of studies examining how selenium supplementation may be relevant in metabolic disorders, including insulin resistance and metabolic syndrome, which is a precursor to type 2 diabetes. Selenium supplementation may also be relevant in connection with various thyroid disorders.

Zinc is involved in several hundred enzymatic processes that are important for cellular signaling, overall health, and the body’s primary antioxidant defenses. Zinc also plays multiple roles in the brain and nervous system. A deficiency of zinc, as well as disturbances in its metabolism, may therefore contribute to the development of Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and other neurodegenerative disorders. In addition, there is evidence that zinc supplementation has therapeutic potential, including the protection of nerve cells and the regeneration of damaged neurons. This is highlighted in a review article published in Molecular Neurobiology.

Cardiovascular disease remains the leading cause of death among kidney patients receiving dialysis, and effective prevention has been lacking. However, it now appears that higher intake of fish oil may reduce the risk of heart attack and stroke by as much as 43%. This is shown in a large placebo-controlled population study published in the New England Journal of Medicine. The researchers note that fish oil also benefits the cardiovascular system in the general population, and that it is especially the omega-3 forms EPA and DHA from fatty fish that have the beneficial effect.

Digestion plays a crucial role in our physical and mental health. Ideally, the bowels should be emptied every day, but constipation and other intestinal disorders such as irritable bowel syndrome (IBS) are very common due to changes in peristalsis, genetic variations, and other factors. According to a large international population study published in BMJ Journals GUT, vitamin B1 has a surprising and positive effect on peristalsis and bowel habits.

Magnesium is one of the minerals we need in the greatest amounts, as it is incorporated into bones and involved in several hundred enzymatic processes that are essential for overall mental and physical health. Magnesium deficiency is very widespread, and because it cannot be detected using standard blood tests, the problem often goes unnoticed. This is highlighted in a review article in which researchers refer to studies showing that magnesium supplementation may be relevant for depression, insomnia, neuropathy, migraine, diabetes, high blood pressure, and several other conditions.

An estimated 2.2 billion people worldwide are deficient in vitamin B1, which is primarily caused by an unbalanced diet, excessive consumption of coffee or tea, various medications, environmental toxins, and genetic defects. The same applies to high alcohol intake, where long-term abuse can lead to life-threatening brain inflammation. Evidence suggests that higher doses of vitamin B1 in supplement form may have a beneficial effect on many symptoms and diseases.

Stroke remains the leading cause of death worldwide. Acute kidney injury is also a common complication that increases the risk of prolonged hospitalization and death. Previous studies have shown that vitamin D deficiency increases the risk of stroke, and it also appears that vitamin D deficiency raises the risk of acute kidney injury and early death following a stroke. This is highlighted in a new study published in Frontiers in Nutrition.

Sepsis is a life-threatening condition and a frequent but underreported cause of death. The condition is caused by a dysregulated immune response to an infection, which can lead to hyperinflammation and organ failure. Diet, lifestyle, and aging processes play a major role in the risk of developing the disease. Previous studies have shown that vitamin D deficiency is a common risk factor. According to a new Chinese study, it appears that vitamin B1 deficiency also increases the risk of developing sepsis. Vitamin B1 deficiency is primarily caused by a refined diet, overconsumption of alcohol, excessive coffee intake, antacids and diuretic medications, as well as genetic defects.