The body’s metabolism encompasses all processes that convert food into energy, as well as those that maintain stable blood sugar levels, normal lipid balance, and normal blood pressure. Metabolic health is therefore crucial in the prevention and management of a range of lifestyle-related diseases. Selenium plays a key role through various enzymatic processes and as a protective antioxidant. Since seleniumdeficiency is widespread, a team of researchers has reviewed a number of studies examining how selenium supplementation may be relevant in metabolic disorders, including insulin resistance and metabolic syndrome, which is a precursor to type 2 diabetes. Selenium supplementation may also be relevant in connection with various thyroid disorders.