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Vitamin A’s key role in wound healing and stem cell biology

Vitamin A’s key role in wound healing and stem cell biologyIn the case of wounds or skin lesions, an active form of vitamin A regulates how stem cells initiate healing processes and produce new skin. This was demonstrated in a study from Rockefeller University that is published in the journal Science. In the future, researchers plan to look closer at how active vitamin A can be used to regulate stem cells as a way of preventing and treating skin cancer.

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Overview of vitamins, minerals, and essential fatty acids

 

Overview of vitamins, minerals, and essential fatty acids

Vitamins, minerals, omega-3 and omega-6 fatty acids, and Q10 are nutrients that we need in certain quantities in order to support vital body functions.
Nutritional supplements containing vitamins and minerals must be labeled in accordance with the reference values.

This overview serves as general information about the different vitamins, minerals, and essential fatty acids and how they work.

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THE VITAMIN AND MINERAL GUIDE

the Vitamin and Mineral Guide

Phosphor (P)

Phosphor (P)An adult person contains around 800-1,200 grams of phosphor. Together with calcium, phosphor is one of the most abundant minerals in the human body and it is vital to maintain the proper balance. About 90 per cent of the body's phosphor is found in our bones and teeth. Phosphor is also an active element of many biochemical processes and even functions as the chemical compound phosphate. Phosphor is regulated in the same way as calcium where vitamin D supports the uptake from the digestive channel, a parathyroid hormone regulates the blood content of the mineral, the kidneys control the excretion, and the bones function as a storage facility.

Functions and importance for

  • Strong bones. Together with calcium and magnesium, phosphor constitutes the solid matter of bone tissue
  • Strong teeth
  • Muscles
  • The brain and nervous system
  • Energy metabolism - a part of ATP (adenosine triphosphate) that is energy stored chemically in molecular form
  • Constituent of cell membranes (as a fatty acid)
  • Constituent of our genetic material (DNA)

Deficiencies and poor utilisation may be caused by

  • Early birth - observed in prematurely born babies
  • Diseases with reduced uptake from the intestine
  • Large intake of aluminum hydroxide that binds phosphor and prevents the uptake of the mineral. Aluminum hydroxide is found in antacids such as Link and Novaluzide

Deficiency symptoms

Rarely seen. This is in part because the diet contains plenty of phosphor but also because our kidneys are able to retain phosphor in situations with deficiency.

  • Poor nerve and brain function
  • Muscle weakness caused by a lack of ATP
  • Reduced appetite and feeling unwell

Long-termt:

  • Decalcification and fragile bones
  • Dental damage

Sources

Phosphor is bound to protein and is found in all types of, especially those rich in protein such as meat, fish, cheese, nuts, and kernels. In grain products and legumes phosphor occurs in the form of inositol hexaphosphate. Phosphoric acid and phosphates are added to certain foods to preserve them. This is seen with soft drinks (especially Coke), certain cheeses, ice cream, candy, breakfast cereals, and meat products such as sausages and bacon.

Phosphor content in mg per 100 grams

Pumpkin seeds 1170
Cheese 530-900
Salmon, cod 200
Chicken, veal 173,178
Cauliflower, chives 53


Recommended daily allowance (RDA)

Adults: 11 years of age and older: 600 mg
Children: 1-10 years of age: 700 mg
Pregnancy and lactation: 700 and 900 mg (respectively)

Overdosing

Overdosing is rarely seen, as the kidneys control phosphor levels. Acute elevated phosphor levels may lead to elevated blood calcium levels that may cause cramps and more serious conditions that are described in the chapter about calcium. Also, see the following section.

Important information

Ingesting too much phosphor in relation to calcium may cause a calcium deficiency, as excess phosphor is excreted in the urine together with calcium taken from the bones. In epidemiological studies, phosphoric acid that is used in various soft drinks (mainly Coke) is associated with lower bone density.

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