Expert task force recommend glucosamine and chondroitin

Expert task force recommend glucosamine and chondroitin A group of leading international experts (ESCEO) says in a new report that glucosamine sulfate in a pharmaceutical grade is safe and effective in the treatment of osteoarthritis and that it can be recommended as a basic treatment of this disorder. Also chondroitin is recommended.

The new expert report provides guidelines for physicians treating patients with osteoarthritis based on the latest research published in recognized scientific journals. The aim is to optimize treatment and to build consensus among doctors about these guidelines.

The new guidelines

These guidelines include providing detailed information to the patient about the disease and its treatment. There is also information about the benefits of losing weight if the patient is overweight, about the benefits of an exercise program, possibly tai chi, by staying active and about the use of pads and insoles, aqua therapy, acupuncture and TENS (electrical nerve stimulation on the skin).

Glucosamine only in pharmaceutical quality

As for the pharmacological treatment of osteoarthritis the expert group recommends glucosamine sulfate in pharmaceutical quality as a safe and sound basis treatmant for pain and joint function in osteoarthritis as it has proven to be superior to placebo. Treatment with glucosamine sulfate did not result in more side effects than those seen in persons who have been given inactive placebo treatment, which in practice makes treatment with glucosamine almost free from side effects.

The expert group does not, however, recommend glucosamine hydrochloride, as they refer to research that has shown no beneficial effect from this type of glucosamine.

Chondroitin also beneficial

Chrondroitin may offer similar benefits on joint structure changes in patients with mild to moderate osteoarthritis. Data has been published that shows chondroitin sulfate to reduce joint structural chances with a symptomatic effect which could be clinically relevant. Also with regard to chondroitin the Panel emphasizes only to use preparations of a high quality.

About ESCEO

ESCEO stands for the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis. It is a non-profit organization engaged in advising physicians and provide them with the latest clinical research in bone, joint and muscle disorders.

The current panel of experts is made up op of 13 international experts in the field of rheumatology, clinical epidemiology and clinical research.

Ref.
Bruyère O, et al. An Algorithm Recommendation for the Management of Knee Osteoarthritis in Europe and Internationally: A Report From a task Force of the European Society for Clinical and Economic Aspects of Osteroporosis and Osteoarthrisis (ESCEO). Seminars in Arthritis and Rheumatism 2014. E-pub ahead of print.

Created on 12 September 2014.

BOOST YOUR IMMUNE DEFENSE

Read about the immune system and how to boost it with the vitamins and minerals that you may be missing in your otherwise health diet

» Low selenium levels in the soil are linked to life-threatening reactions to COVID-19

» News: Intravenous zinc therapy for patients with COVID-19

» Are vitamin D supplements able to protect against COVID-19 and other infections?

» The war against COVID-19 requires four nutrients, which many people lack

» Lack of selenium increases your risk of viral infections and could even make them more dangerous

» Lack of vitamin D increases your risk of virus infections and sequela

» Coronavirus and new hope: Vitamin C for prevention and intravenous therapy in the case of life-threatening complications

» Strengthen your immune system with vitamin C

» Vitamin D prevents influenza and respiratory infections

» Selenium can prevent infections and cancer

» Zinc counteracts infections, eczema, and herpes

Search

Q10 goes by many names

Q10 is known by so many different names that one easily gets confused. Here is a list of the many synonyms for Q10 in its two forms:

Q10 goes by many names

Ubiquinone:
◊ Oxidized Q10 ◊ Normal Q10 ◊ CoQ10 ◊ Ubikinon ◊ Ubiquinone ◊ Ubidecarenone ◊ 2,3-dimethoxy-5-methyl-6-polyprenyl-1,4-benzoquinone

Ubiquinol:
◊ Reduced Q10 ◊ Active Q10 ◊ CoQH ◊ Ubikinol ◊ Ubiquinol ◊ QH ◊ QH2 ◊ QX ◊ 2,3-dimethoxy-5-methyl-6-polyprenyl-1,4-benzoquinol

Is there really a difference? Is ubiquinol better than ubiquinone?

Read the article:
Ubiquinone or Ubiquinol - does it really matter?

Check this before you buy a Q10 product

Bio-availability and documentation are key points

Check this before you buy a Q10 product

Studies show that the best bio-availability is obtained when the active compound is dissolved in an oil of some sort and encapsulated in soft, light-protected (light destroys Q10) gelatin. There are many products out there that meet these requirements. However, this is not in any way a guarantee that they are absorbed well. The only way to make sure that a product has good bio-availability and is safe for consumption is to contact the manufacturer and ask for documentation for the following:

- that the product is non-crystalline

Q10 as a raw material consists of crystals which are not easily absorbed in the digestive system. It is therefore vital to transform the Q10 raw material to a homogenous and assimilable form that can ensure good bio-availability in the body. This would require the Q10 to be dispersed in oil, just like it would require the manufacturer to be familiar with the technique and patented method employed to change the Q10 molecules into a non-crystalline form.

- that the product is nature-identical

This entails that the Q10 molecules in the product are completely identical with the Q10 that the human body synthesizes in relatively small quantities. The body is not able to distinguish between nature-identical Q10 and the endogenously synthesized Q10.

Are you taking supplements

- be careful and choose the right preparations

Are you taking supplements

It can be really difficult to know if a nutritional supplement has the quality required to be absorbed and utilized by the body.

Read on and find out what specifically to look for

Weight loss that works

- and lasts in the long run

Weight loss that works It is a myth that the only way to obtain or maintain your ideal weight is to stick with boring, low-fat diets and loads of hardcore physical training.